Indole-3-Carbinol

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Indole-3-Carbinol supports female reproductive health by facilitating estrogen metabolism in the liver*

Indole-3-Carbinol 60 caps SF749

Indole-3-Carbinol Details

Cruciferous vegetables, including broccoli, cauliflower, Brussels sprouts, and cabbage, contain a compound called indole-3-carbinol (I3C).* As a nutritional supplement, I3C provides key nutritional support for the liver’s detoxification of estrogens, thus playing an important role in supporting female reproductive health.* A large portion of I3C is converted to diindolylmethane (DIM), the substance believed to be the primary contributor to I3C’s beneficial properties. DIM has been shown to selectively bind to estrogen receptors and might act as an estrogen antagonist.*

In the liver, I3C promotes the metabolism of estrogen and increases the ratio of 2-hydroxy estrogen to 16-hydroxy estrogen.* The 2-hydroxy estrogens, which are less active than the 16-hydroxy estrogens, are generally eliminated more quickly from the body. One study found postmenopausal women who had the most favorable 2:16-hydroxy estrogen ratio were most likely to maintain good female health.* Studies have examined the efficacy, safety, and optimal supplementation of I3C. A 12-week trial conducted on 17 women found a 66-percent increase in the 2:16-hydroxy estrogen ratio with administration of 400 mg of I3C daily.*

Warnings

ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY
If pregnant, consult your health professional before using this product.

INTERACTIONS
There are no known adverse interactions or contraindications at publication date.

Key Ingredients

Indole-3-Carbinol

Ingredient Amounts

Serving Size: 1 Capsules
Servings Per Container: 60
Name Amount
Indole-3-Carbinol 200mg
Other Ingredients: Hypromellose Capsule, Leucine, Microcrystalline Cellulose, Silicon Dioxide

Thorne Verified

Derived From Natural Flavors
Derived From Natural Colors
Gluten Free
Dairy Free
Soy Free

How to Use

Take 1 capsule one to two times daily or as recommended by your health professional.

Contact us for a Functional Medicine consultation.

 

Weight 12 oz
Dimensions 5 in
Size

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