Cortisol Manager 30 tabs (70453) and 90 tabs (70459)

The ingredients in Cortisol Manager support healthy cortisol levels.* Cortisol is one of the most important hormones involved in the adaptation process. By supporting balanced cortisol and a healthy stress response, Cortisol Manager also promotes relaxation to support restful sleep.*

THE ROLE OF CORTISOL IN TIMES OF STRESS

Cortisol is a hormone produced in the adrenal cortex that is released during times of stress. Variations in cortisol secretion can indicate how well the body is coping with stress. Cortisol homeostasis is typically characterized by peak secretion during the early morning hours with a gradual decline throughout the day. Because of its central role as a key stress hormone, cortisol is often thought of as a bridge between stress and its health impact.

WITH HERBAL INGREDIENTS

The ingredients in Cortisol Manager help support a balanced, adaptive cortisol response to stress.* Cortisol Manager contains a stress-reducing proprietary blend of Sensoril® brand ashwagandha (Withania somnifera) and L-theanine.* A proprietary blend of Magnolia (Magnolia officinalis) and epimedium (Epimedium koreanum), as well as phosphatidylserine from soy lecithin are included in Cortisol Manager.

A 2008 placebo-controlled clinical trial showed that Sensoril® ashwagandha significantly reduced serum cortisol levels and helped manage stress compared to placebo, in subjects experiencing higher levels of stress.*¹ A 2018 placebo-controlled clinical trial showed that a single intake of L-theanine significantly increased alpha brain wave activity in subjects compared to their placebo counterparts.*² Alpha brain wave activity is associated with a more relaxed mental state.*²

The ingredients in Cortisol Manager help support relaxation to promote restful sleep.* They also help stabilize the stress hormone cortisol to further support a healthy stress response.*

REFERENCES

1. Auddy B et al. J Am Nutraceutical Assoc. 2008;11(1):50-6.
2. Nobre AC et al. Asia Pac J Clin Nutr. 2008;17(S1):167-68.
   

   Ingredients

   Serving Size: 2 tablets

   Amount/Serving

   %DV

   Calories

   10

   …

   Total Carbohydrate

   1 g

   <1%†

   Sodium

   10 mg

   <1%

   Stress-Reducing Proprietary Blend: Ashwagandha (Withania somnifera) (Sensoril® brand) (root, leaf) Extract, L-theanine

   500 mg

   **

   Cortisol-Reducing Proprietary Blend: Magnolia (Magnolia officinalis) (bark) Extract standardized to 2% honokiol and 1% magnolol, Epimedium (Epimedium spp.) (aerial parts) Extract

   450 mg

   **

   Phosphatidylserine (from soybean lecithin)

   100 mg

   **

   ** Daily Value (DV) not established

   †Percent daily value is based on a 2000 calorie diet

   Other Ingredients

   cellulose, sodium croscarmellose, stearic acid, calcium silicate, magnesium stearate, silica, hypromellose, glycerin

   Cortisol Manager® Does Not Contain

   • Gluten
   • Dairy
   • Wheat

   Other Details

   Sensoril® is a registered trademark of Natreon, Inc. and is protected under U.S. Patent No. 7,318,938.

   Quality Global Sourcing

   UPC: 00871791003811

   Directions

   Cortisol Manager® Directions and/or Dosage

   Adults take 1 tablet before bedtime or as recommended by a healthcare professional. Increase to 2 tablets during times of high stress. For nightly use.

   Warning

   Do not use if you are pregnant or nursing. If you are taking any medications, consult a healthcare professional before use. Individuals with diabetes should monitor blood glucose levels closely while taking this product.

   Keep out of reach of children.

   Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

   FAQs

   • Q. Can Cortisol Manager® be taken during the day? Will it cause drowsiness?

     A. While some individuals do take Cortisol Manager® during the day, caution should be used as it will cause you to relax and drowsiness may occur.†

   • Q. Can Cortisol Manager® be helpful for someone with low cortisol levels?

     A. While the ingredients do have a modulating effect, the small scale study shows a rather significant reduction in cortisol levels. Therefore, we would not recommend Cortisol Manager® for someone with low cortisol.

   • Q. What is the source of the phosphatidylserine in Cortisol Manager®?

     A. The source of the phosphatidylserine in Cortisol Manager® is vegetable glycerin. The glycerin, in turn, is derived from a highly purified, refined soybean oil, which contains no allergenic proteins.

   • Q. Can Cortisol Manager be used in mid or late-stage stress response?

     A. Though typically used within the early-stage of the stress response, Cortisol Manager can be used in the mid and late stages – particularly within the mid-stage when additional energy and stress support is needed.* The HPA Optimization program highlights key nutrient support that is appropriate for the mid and late stages, such as the adaptogenic herbal combination of HPA Adapt, for mid-stage, and CortiVive for late stage, which supports healthy cortisol production and healthy adrenal cortex function.

   • Q. As a member of the nightshade family, does ashwagandha pose any potential dangers or side effects?

     A. No, not when used properly. Research has shown that ashwagandha offers safe and effective support for the body during times of stress.* Unfortunately, there are some sources indicating that all plants of the Solanaceae or nightshade family (potatoes, tomatoes, peppers, eggplant, and ashwagandha, included) should be avoided because of their potential to reduce immune system function. However, many of these same plants and herbs have been used as food staples and medicines for thousands of years. These compounds, found in green part of the vegetables, may cause adverse effects in humans when taken at unrealistically high levels.

     Dairy-free, Gluten-free